MangaStudio handles tablet input interestingly--the line comes out thick and then kind of 'bounces' or snaps back to the proper pressure-adjusted weight. The results do look like something you'd get from a real ink pen, though. Definitely takes some getting used to, but it's an interesting tool, and helps me ink nice and fast.
Another feature that I like is how it handles panels--you can generate panels just by throwing down some lines, and you can make each panel its own layer group automatically. Text support is actually kind of weird (if you change the properties of some text and then make any additions to that text, the new characters come out in default font, which is pretty annoying), but again the software can generate dialogue balloons for you, which is a lifesaver.
New page coming up tonight.