What he wants is something that scales the screen so he can play it fullscreen on his TV.
I understand what he's saying. And anyway, trying to upscale the game only to output it to a TV is completely unnecessary. You're just scaling the 640x480 game to 800x600, then scaling it back down to 486 lines of resolution. It's like trying decompress a crappy mp3 to a wave file, only to recompress it to something else at a high bitrate. You're not just making what you had unnecessarily bigger, but you're losing quality and CPU resources in the process.
Also, using an S-Video cable doesn't give you higher resolution, it just means you're not combining all the different signals together like you would with a composite video cable. So it's clearer but still standard NTSC resolution.
If you were outputting to a computer monitor I'd understand scaling the picture up, but not for a standard NTSC TV monitor.
Just set the game and HyperSpin to 640x480. Doing anything else will be totally unnecessary.
(Sorry, I forgot that the games do only 640x480 in fullscreen, ahahaa.)