also wood enemies rip
well obviously I'd combo higher if needed, but not every boss has combo shield
And wood enemies aren't really a specific problem now that even light and dark are getting resisted a lot
Anyways for optimal subs, Reine + Andro are pretty much shoe ins, as is Karin for the full board.
The final sub doesn't actually need to be fire because you only need to match 3 atts anyways. If you ditch fire then you have the same activation difficulty as the leader version of the chinese girls (need 3 out of 4 specifics) which is still really easy.
That way you have a ton of options for the final sub like more orb changers like Hatsume, more rows with Bodin, more full boards with another Karin, or even 100% shield + activation rate with another Awoken Isis :V
Now I just need a Karin though >_>