I've only tried MIDI with EoSD, and honestly, it's kinda interesting. Some songs are worse, some are better. Personally, I think Remilia's track to sound better using MIDI.
That being said, MIDI doesn't always have bad or strange quality sounds, MIDI itself is really little more than just another way to write music (it's not actually just music but whatever), the actual sounds of all the virtual instruments and whatever are NOT part of MIDI, people think they are because the general MIDI sound library is the same across many platforms, and yes, they all suck hard. But you can get a really amazing MIDI sound too, and chances are alot of the wave files you know and love have MIDI recordings within those wave files.
