You don't need to guess in that example.
01?? 01X?
01?? 01X?
13?? 13X?
2M?? 2MXY
2M3? 2M3Y
112? 112Y
The lower 3 spaces marked X have 2 mines, the upper 3 have 1. Therefore the middle 2 both can not contain a mine, meaning the lowest X is a mine. This gives 3 mines adjacent to the 3 at the bottom clearing the spaces marked Y. Additionally the top X is guaranteed safe.
I've just gone and played it a bit myself, ran into a place where I had to guess once.
Overall thoughts...Marisa overlapping the number proved annoying, I had to move my mouse cursor to see the number. The "GREAT" on clearing a 0 was annoying as well because it's a visual distraction, though that's a minor gripe.
How long does Patchy stick around for? Also, while messing with Patchy, I came across
this. What happened there, there should be a mine in that spot but there isn't, is this a glitch or did it happen because I didn't flag everything :V
edit: Having to flag everything is a real nuisance since NF play is a thing.