Cookie wiki says it takes sometihng in the order of 150 days to get 100 of those.
After you get the golden cookie upgrades, almost all of your cookies will come from Golden Cookies.
After you get the first two golden cookie upgrades, if not before, you'll want to save up enough in your bank for the "Lucky!" effect (which grants 10% of your bank) to max out (When your bank is holding at least 5 hours worth of passive cookie generation). At that point clicking golden cookies now and then will dwarf your passive cookie production entirely; you'll have a golden cookie every 2~3 minutes and the Lucky! bonus will grant you a half hour's worth of cookie production immediately.
Then, when you get the THIRD golden cookie upgrade, Get Lucky, you'll be able to overlap Frenzy and Lucky! to get a Lucky! that's seven times as strong (plus your frenzies will give twice as much) so Get Lucky is by far worth the 77t cost and will pay itself off in no time, I get like 11t per frenzied Lucky
In this update he changed the golden cookie algorithm to drastically lower the chances of getting the same effect twice in a row, so getting a Frenzied Lucky is a lot more common then you might think.
I'm gonna hit 1 billion CpS tonight, probably. B)