10-5 no item is micro, micro with RNG, super micro, dodge in a corner, micro, dies.
With an item you can use a substitute jizo on the first 4 waves (or dodge the first and blast through waves 2-4) and just clear it easily.
Guys, how do I do 4-3 and 4-6? :V
Abuse doll sub on the first for massive damage, I've been shown a replay of killing it in 2 waves with a lot of luck-I killed it in 4 waves, since I approached the dodging in a more consistent manner (dodging on the side the butterflies first spawn on).
4-6 is pretty nasty, you can either flail, read it or do what Serela discovered and move down as they approach. I haven't personally done this (did a combo of flail and read), but I heard it works.